Research

• Isolation and characterization of biologically important proteins, glycoproteins, peptides, glycopeptides, and glycolipides;

• Conventional and enzymatic catalyzed synthesis of biological active peptides;

• Photosensitizing and fluorescent dyes in red and far-red spectra region - synthesis and studies of their main properties as diagnostic and therapeutic agents;

• Development of the so called photodynamic method, based on the photochemical processes, for inactivation of bacteria and viruses in clinical practice and ecology;

• Fluorescent probes, based on the highly conjugated compounds, like phthalocyanines and derivatives, for study of the protein's structures;

• Immobilization of biocatalysts, modification of natural oils and investigation of lipase inhibitors for medical and cosmetics purposes;

• Isolation and purification of enzymes from microbial origin for nutrient and fodder purposes and cosmetics;

• Preparation of technology for protein hydrolysates with designed properties for application in medicine and sport as food additives;

• Application of fluorescent methods for determination of antioxidant activity of biological materials;

• Production and characterization of novel materials (hemocyanins) for prevention of virus infection;

• Evaluation of the antioxidant potential of natural objects by means of spectrophotometric and fluorometric methods. Investigation of the impact of the oxidative stress on the properties of connective tissue proteins. Modification of known methods for proving of dye substances and traces of leather in archaeological and museum objects for the purposes of the conservation analysis.

Laboratory members

Head:

Assoc. Prof. Maya Guncheva, PhD

02 9606 160

408

maiag@orgchm.bas.bg

Name	Room	Phone	Е-mail*
Assoc. Prof. Maya Guncheva, PhD, Head	408	160	maiag
Prof. Pavlinka Dolashka-Angelova, PhD	403	163	dolashka
Assoc. Prof. Aleksandar Dolashki, PhD	417	155	adolashki
Assoc. Prof. Ivan Angelov, PhD	211	181	ipangelov
Assoc. Prof. Krassimira Idakieva, PhD	216	190	idakieva
Assoc. Prof. Lyudmila Velkova, PhD	403	163	lyudmila_velkova
Assoc. Prof. Miroslav Rangelov, PhD	201	161	marangelov
Assoc. Prof. Vanya Mantareva, PhD	211	181	mantareva
Assist. Prof. Dancho Yordanov, PhD	418	175	danchoyordanov
Assist. Prof. Yuliana Raynova, PhD	216	190	yulianaraynova
Assist. Boryana Yakimova	408	160	byakimova
Assist. Venceslav Atanasov	403	163	vatanassov
Alla Bynkova, chemist	418	175	allabynkova
Asya Daskalova, chemist	403	163
Dimitar Kaynarov, chemist	403	163	dkaynarov
Plamen Hristov, chemist	214	174	plamen62
Proletina Kardaleva, chemist	417	155	pkardaleva
Adelina Makedonska, technician	403	163	amakedonska
Nikol Zhelyazkova, technician	408	160

PROJECTS

SELECTED GROUP PUBLICATIONS(Q1):

2018

Metallomics,
10,
659-678

Interaction of Na⁺, K⁺, Mg²⁺ and Ca²⁺ counter cations with RNA